New! CurraNZ Immune, for targeted, natural support

With the explosion in the scientific understanding of plant phytochemicals for health and immunity, we are proud to launch CurraNZ® Immune Support, an expertly formulated 100% natural food supplement blend of bioactives from polyphenols, botanicals, vitamins and minerals.

Featuring the powerful Immuno3B^TM super-complex, CurraNZ® Immune Support is a proprietary formulation of nutrient-dense botanical polyphenol compounds courtesy of CurraNZ® blackcurrant 35% extract, plus blueberries and elderberries.

These hero botanical compounds, called anthocyanins, are responsible for delivering the immune-enhancing effects and help prevent opportunistic infections (8,9).

Completing the Vegan-friendly formulation, are nature-identical sources of Vitamins C, D, A, Beta Glucans and Selenium, which are important contributors to the normal function of the immune system.

The broad-spectrum properties of Anthocyanins 

The anthocyanins in our Immuno3B^TM complex have diverse and complex modes of action. They interact with a specific type of immune T cell - an important arm of the immune system - to activate both innate and acquired immunity and support mucosal defences (1,2). 

As well as supporting immune function, anthocyanins multi-task as antioxidants, and therefore doubly beneficial because they prevent damage to surrounding tissues caused by Reactive Oxygen Species (ROS), which is generated by inflammation (7-9).

Studies have found that symptoms of colds and Influenza may be shorter and less severe with elderberry supplementation, compared to placebo (10).

Each capsule of CurraNZ® Immune Support contains the equivalent of 2,500mg of fresh blackcurrants, blueberries and elderberries.

Acerola cherry 

Free of synthetic ingredients, the Vitamin C used in CurraNZ® Immune Support is sourced from cherry, to perfectly complement the berry botanicals in this natural supplement.

Acerola cherry is one of the richest natural sources of ascorbic acid ­(Vitamin C) – around 50–100 times than that of oranges or lemons ­– and also contains a plethora of phytonutrients like anthocyanins (11-12).

Beta-glucans have been used in traditional Chinese medicine as immunomodulators for centuries. These groups of polysaccharides (complex sugars) are sourced from brewer’s yeast. As with anthocyanins, they act to trigger the host’s immune responses and enhance innate immune memory, whilst protecting against bacterial re-infection (13).

Vitamin D (from mushroom) plays a crucial role in the proper functioning and activation of the immune system — the first line of defence against infection and disease. Each capsule provides a healthy dose - 200% NRV - to activate immune system function. Vitamin D has both anti-inflammatory and immunoregulatory properties and enhances T-cells and macrophage activity, which protects your body against pathogens (14).

Vitamin A (from beta carotene), is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium (cells that protect and enclose organs) and mucus integrity in the body. Vitamin A is known as an anti-inflammation vitamin because of its critical role in enhancing immune function (15)

Selenium, (selenium-rich yeast), plays an important role in the health of the immune system, with each capsule providing 100% NRV. This antioxidant helps lower oxidative stress in your body, which reduces inflammation and enhances immunity.

Studies have demonstrated that increased blood levels of selenium are associated with enhanced immune response (16).

CurraNZ® Immune Support Ingredients

Capsule Shell (Hydroxypropyl Methylcellulose), Acerola (Vitamin C, from cherry), Beta Glucans, Blueberry Extract, Elderberry Extract, CurraNZ Blackcurrant Extract, Selenium Yeast, Beta Carotene, Vitamin D3.

Directions for use

Take 1-2 capsules daily with water.

Can be used a companion supplement to CurraNZ Original. 

REFERENCES 

1. Percival, S. S. (2009). Grape consumption supports immunity in animals and humans. J Nutr, 139(9), 1801S-1805S. doi: 10.3945/jn.109.108324
2. Denev, P., Kratchanova, M., Ciz, M., Lojek, A., Vasicek, O., Nedelcheva, P., Vojtek, L. (2014). Biological activities of selected polyphenol-rich fruits related to immunity and gastrointestinal health. Food Chem, 157, 37-44. doi: 10.1016/j.foodchem.
3. Hurst RD, Lyall KA, Roberts JM, Perthaner A, Wells RW, Cooney JM, Jensen DJ, Burr NS, Hurst SM. Consumption of an Anthocyanin-Rich Extract Made From New Zealand Blackcurrants Prior to Exercise May Assist Recovery From Oxidative Stress and Maintains Circulating Neutrophil Function: A Pilot Study. Front Nutr. 2019 May 29;6:73. doi: 10.3389/fnut.2019.00073. PMID: 31192216; PMCID: PMC6548855.
4. Microbiol Immunol 2012; 56: 805–809 doi:10.1111/j.1348-0421.2012.00510.x ORIGINAL ARTICLE Anti-viral and anti-bacterial activities of an extract of blackcurrants (Ribes nigrum L.) Kazufumi Ikuta1, Koichi Hashimoto1, Hisatoshi Kaneko1, Shuichi Mori1,2, Kazutaka Ohashi1 and Tatsuo Suzutani1
5. Ikuta K, Hashimoto K, Kaneko H, Mori S, Ohashi K, Suzutani T. Anti-viral and anti-bacterial activities of an extract of blackcurrants (Ribes nigrum L.). Microbiol Immunol. 2012 Dec;56(12):805-9. doi: 10.1111/j.1348-0421.2012.00510.x. PMID: 22985050.
6. Mohammadi Pour P, Fakhri S, Asgary S, Farzaei MH, Echeverría J. The Signaling Pathways, and Therapeutic Targets of Antiviral Agents: Focusing on the Antiviral Approaches and Clinical Perspectives of Anthocyanins in the Management of Viral Diseases. Front Pharmacol. 2019 Nov 8;10:1207. doi: 10.3389/fphar.2019.01207. PMID: 31787892; PMCID: PMC6856223.
7. Steffen, Y., Gruber, C., Schewe, T., & Sies, H. (2008). Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch Biochem Biophys, 469(2), 209-219. doi: 10.1016/j.abb.
8. Prior, R. L., Cao, G., Martin, A., Sofic, E., McEwen, J., O'Brien, C., Mainland, C.M. (1998). Antioxidant Capacity As Influenced by Total Phenolic and Anthocyanin Content, Maturity, and Variety of Vaccinium J Agric Food Chem, 46(7), 8.
9. Gomes-Rochette, N. F., Da Silveira, Vasconcelos, M., Nabavi, S. M., Mota, E. F., Nunes-Pinheiro, D. C., Daglia, M., & De Melo, D. F. (2016). Fruit as Potent Natural Antioxidants and Their Biological Effects. Curr Pharm Biotechnol, 17(11), 986-993. Domitrovic, R. (2011). The molecular basis for the pharmacological activity of anthocyans. Curr Med Chem, 18(29), 4454-4469.
10. Hawkins, Jessie, et al. "Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials." Complementary therapies in medicine42 (2019): 361-365.
11. Belwal T, Devkota HP, Hassan HA, Ahluwalia S, Ramadan MF, Mocan A, Atanasov AG. Phytopharmacology of Acerola (Malpighia spp.) and its potential as functional food. Trends in food science & technology. 2018 Apr 1;74:99-106.
12. Mezadri T, Villaño D, Fernández-Pachón MS, García-Parrilla MC, Troncoso AM. Antioxidant compounds and antioxidant activity in acerola (Malpighia emarginata DC.) fruits and derivatives. Journal of Food Composition and analysis. 2008 Jun 1;21(4):282-90.
13. Volman JJ, Ramakers JD, Plat J. Dietary modulation of immune function by β-glucans. Physiology & behavior. 2008 May 23;94(2):276-84.
14. Jolliffe DA, Camargo Jr CA, Sluyter JD, Aglipay M, Aloia JF, Ganmaa D, Bergman P, Bischoff-Ferrari HA, Borzutzky A, Damsgaard CT, Dubnov-Raz G. Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials. The Lancet Diabetes & Endocrinology. 2021 May 1;9(5):276-92.
15. Ross AC. Vitamin A and retinoic acid in T cell–related immunity. The American journal of clinical nutrition. 2012 Nov 1;96(5):1166S-72S.
16. Avery JC, Hoffmann PR. Selenium, selenoproteins, and immunity. Nutrients. 2018 Sep;10(9):1203.